In 2009, PacBio published a paper expanding the principle into a full-blown sequencing technique. Once again, each nucleotide was labeled with a different colored fluorophore detectable by the ZMW to determine which base had been incorporated. The fluorophores were attached such that they would be cleaved off during the chemical reaction incorporating the base into the growing DNA strand; they would then diffuse out of the ZMW so that the next fluorophore could be detected. Sequencing took place on a chip with many wells simultaneously — a different type of parallelization where each well detected a single DNA molecule undergoing the same basic chemical reaction.
Credit: Timothy Werth / Mashable
。业内人士推荐heLLoword翻译官方下载作为进阶阅读
Фото: Inna Varenytsia / Reuters
Сын Алибасова задолжал налоговой более 1,8 миллиона рублей20:37
，更多细节参见谷歌浏览器【最新下载地址】
If you’ve been trying to grab a Mega Evolution ETB without paying the usual $100+ markups, Walmart just helped out your trading card budget.
Opens in a new window，详情可参考PDF资料